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Filtering surgery (0)     12.8.1 Without tube implant (29)     12.8.2 With tube implant or other drainage devices (78)     12.8.3 Non-perforating (8)     12.8.4 Using laser (0)     12.8.5 Other (8)     12.8.10 Woundhealing antifibrosis (15)     12.8.11 Complications, endophthalmitis (17)   12.9 Trabeculotomy, goniotomy (27)   12.10 Cyclodestruction (17)   12.11 Cyclodialysis (1)   12.12 Cataract extraction (0)     12.12.1 Intracapsular (0)     12.12.2 Extracapsular (0)     12.12.3 Phacoemulsification (14)   12.14 Combined cataract extraction and glaucoma surgery (0)     12.14.1 Intracapsular (0)     12.14.2 Extracapsular (0)     12.14.3 Phacoemulsification (22)   12.15 Capsulotomy (0)   12.16 Vitrectomy (8)   12.17 Anesthesia (3)   12.20 Other (1) 13 Therapeutic prognosis and outcome (0)   13.1 Prognostic factors (1)   13.2 Outcome (0)     13.2.1 IOP (0)     13.2.2 Visual field (0)       13.2.2.1 Progression (0)       13.2.2.2 Improvement (1)     13.2.3 Other (0) 14 Costing studies; pharmacoeconomics (10) 15 Miscellaneous (32)

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Abstract #92586 Published in IGR 22-1

The Effects of Glaucoma and Glaucoma Therapies on Corneal Endothelial Cell Density

Realini T; Gupta PK; Radcliffe NM; Garg S; Wiley WF; Yeu E; Berdahl JP; Kahook MY
Journal of Glaucoma 2021; 30: 209-218

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A healthy corneal endothelium is required for corneal clarity. Both the glaucoma disease state and its various forms of treatment can have adverse effects on the corneal endothelium. Both the presence of glaucoma and the magnitude of intraocular pressure elevation are related to endothelial cell loss (ECL). Topical medical therapy, laser procedures, and both traditional surgeries-trabeculectomy and tube-shunts-and newer minimally invasive glaucoma surgeries have variable effects on ECL. This review will summarize the reported effects of glaucoma and its treatment on ECL. Concerns for corneal endothelial cell health should be part of the decision-making process when planning glaucoma therapy for lowering intraocular pressure, with added caution in case of planned device implantation in eyes with preexisting ECL and low endothelial cell density at high risk for corneal endothelial decompensation.

Department of Ophthalmology and Visual Sciences, West Virginia University Eye Institute, Morgantown, WV.

Full article

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Classification:

2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
12.1 General management, indication (Part of: 12 Surgical treatment)

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