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Abstract #92592 Published in IGR 22-1
Clinical and Specular microscopy characteristics and corelation in Iridocorneal endothelial syndrome without corneal edema
Chaurasia S; Choudhari NS; Mohamed ASeminars in Ophthalmology 2021; 0: 1-8
PURPOSE: To investigate endothelial imaging patterns in ICE syndrome and correlate these with the observed clinical features in the affected eye. METHODS: Of the 70 patients of ICE syndrome referred from the glaucoma clinic between 2017 and 18, 17 patients had a clear cornea for reliable endothelial imaging were included in the study. RESULTS: Mean age was 47(range 29-63) years; 9 males and 8 females. The right eye was involved in 10 and left eye in 7 patients. Mean best corrected visual acuity was 20/30 (20/20-20/80) in the affected eye. All 17 patients had clear and compact central cornea and reasonably good vision at the time of specular microscopy. Those with best corrected visual acuity <20/20 had cataract as a co-morbidity. Endothelial abnormalities were noted in all patients and were documented using Hirst and modified Sherrard's classification system. As per the modified Sherrard's classification system, 9 eyes were categorised into total ICE, 5 eyes into subtotal ICE, in 3 eyes grading could not be applied. Of the 4 subtotal ICE, 1 was subtotal ICE (+) and 3 were subtotal ICE (-). 12/17 patients had glaucomatous disc. CONCLUSIONS: Specular microscopy provides information on the various morphological pattern of endothelial abnormalities and helps in mapping out the areas with abnormal/diseased endothelium. These have implications in the management of ICE syndrome.
The Cornea Institute, L V Prasad Eye Institute, Hyderabad, India.
Full articleClassification:
9.4.2.1 Iridocorneal endothelial syndrome (ICE, incl. irisatrophy) (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
