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Abstract #94258 Published in IGR 22-2
Incidence and Risk Factors of Ocular Hypertension and Glaucoma in Patients With Acanthamoeba Keratitis
Al Owaifeer AM; Al-Omair S; Alrefaie S; AlEnezi SH; Al-Shahwan SEye Contact Lens 2021; 47: 588-591
OBJECTIVES: To determine the incidence of ocular hypertension (OHT) and glaucoma in patients with acanthamoeba keratitis (AK) and to outline the risk factors for the development of glaucoma. METHODS: A retrospective review of patients diagnosed with AK at our institute during the period from 2000 to 2018. The main outcome measures were the incidence of OHT and glaucoma, and risk factors for the development of glaucoma. RESULTS: Fifty-two eyes diagnosed with AK were included. The incidence of OHT and glaucoma was 51.9% and 32.7%, respectively. The mean duration from disease onset to the first attack of elevated intraocular pressure was 8.4±16.6 months. The use of corticosteroids in the treatment regimen was significantly associated with the development of glaucoma (odds ratio, 3.93; 95% confidence interval, 0.96-16.15; P=0.049). At the last follow-up visit, both patients with glaucoma and nonglaucoma patients had improved visual acuity without a difference in the mean amount of logarithm of the minimum angle of resolution acuity improvement among them (0.56±0.91 vs. 0.67±0.87, P=0.686). CONCLUSION: Our findings confirm that OHT and glaucoma are frequent complications in AK. Patients treated with a regimen containing corticosteroids are at a higher risk; thus, they should receive close intraocular pressure monitoring.
King Khaled Eye Specialist Hospital (A.M.A.O., S.A., S.A.-S.), Riyadh, Saudi Arabia; Ophthalmology Unit (A.M.A.O., S.A.-O.), Department of Surgery, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia; and Department of Ophthalmology (S.H.A.), College of Medicine, Majmaah University, Majmaah, Saudi Arabia.
Full articleClassification:
9.4.2.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)