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Abstract #94641 Published in IGR 22-2

Topiramate-induced Acute Transient Myopia and Angle Narrowing

Khan S; Ashraf A; Javaid H; Khizer MA
Journal of the College of Physicians and Surgeons Pakistan 2021; 30: 728-731


Sulphamate drugs, widely prescribed for various systemic conditions, are reported to have rare ocular adverse-effects, usually within weeks of initiation of treatment. Medical and drug history in such cases are of pivotal importance in reaching a proper diagnosis. This study reports three cases, which developed topiramate-induced ocular side effects. In one of the cases, although the angles were narrow in both eyes, yet intra-ocular pressure (IOP) was not high. Also, in the third case, there were no macular striae. Topiramate was immediately withheld and all cases were improved without any permanent ocular damage. Key Words: Sulphamate, Topiramate, Angle closure glaucoma, Myopia.

Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.

Full article

Classification:

9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
8.1 Myopia (Part of: 8 Refractive errors in relation to glaucoma)



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