advertisement
Abstract #95343 Published in IGR 22-2
Brachytherapy for Peripheral Retinal Capillary Haemangioblastoma in von Hippel-Lindau Disease
Dalbah S; Bechrakis NE; Thomasen H; Flühs D; Flühs D; Rating P; Guberina M; Guberina M; Stuschke M; Stuschke M; Fiorentzis M; Bornfeld N; Bornfeld N; Biewald E; Biewald EKlinische Monatsblätter für Augenheilkunde 2021; 238: 781-787
AIM: To report our experience with ruthenium-brachytherapy of peripheral capillary haemangioblastomas in patients with von Hippel-Lindau disease. DESIGN: Retrospective case series. METHODS: A total of 53 haemangioblastomas, treated with ruthenium-brachytherapy, were included in our study. The applied radiation dose, visual outcome, angioma activity, need for vitreoretinal surgery and incidence of secondary complications such as macular oedema, secondary glaucoma, vitreous haemorrhage, and epiretinal gliosis were assessed. RESULTS: All treated eyes could be preserved. In 11 patients (20.8%), single brachytherapy did not achieve complete inactivation of the tumour. 31% developed macular oedema postoperatively. Tractional retinal detachment developed in 23.8%, and epiretinal gliosis was observed in 2.4% of patients. Vitreoretinal surgery was necessary in 50% of all treated eyes. At the end of the follow-up, 40.5% of all treated eyes achieved visual acuity (VA) of 0.6 or better, and one third reached a VA of less than 0.1. Mean irradiation dose to the tumour apex was 144 Gy. Higher apex doses correlated with better tumour control of irradiated haemanigoblastomas and lower complication rates. CONCLUSIONS: Brachytherapy of peripheral retinal capillary haemangioblastomas is an effective treatment modality. Higher irradiation doses seem to lead to more successful treatment.
Klinik für Augenheilkunde, Universitätsklinikum Essen, Deutschland.
Full article