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Abstract #96000 Published in IGR 22-3
The therapeutic effect of Healaflow in glaucoma surgery
Wu L; Liu J; Chang X; Zheng YAmerican journal of translational research 2021; 13: 9729-9735
OBJECTIVE: To explore the clinical effectiveness of Healaflow in primary angle-closure glaucoma surgery. METHODS: From August 2018 to July 2019, 100 primary angle-closure glaucoma patients admitted to our ophthalmology department were divided into a control group (trabeculectomy alone) and an observation group (trabeculectomy + Halver), with 50 patients in each group, and 53 eyes in the control group and 56 eyes in the observation group. All the patients were followed up for half a year. The vision, intraocular pressure, bleb morphology, efficacy, and adverse reactions were evaluated. RESULTS: There was no significant difference in the visual acuity between the two groups of patients during the follow-up (P > 0.05). The intraocular pressure levels in the two groups of patients during the follow-up were significantly lower than they were before the treatment (P < 0.05), and the difference in the intraocular pressure levels between the 6th month postoperative groups was significant (P < 0.05). During the last follow-up, 45 eyes in the control group developed functional filtration blebs, and 8 eyes had non-functioning filtration blebs. There were 55 functional filtration blebs and 1 non-functional filtration bleb in the observation group ( = 4.731, P = 0.030). The total effective rate in the observation group was higher than it was in the control group (92.86% VS 77.36%, = 4.058, P = 0.044). During the follow-up period, the control group had 2 eyes with anterior chambers, 1 eye with low intraocular pressure, and 1 eye with an iris adhesion. The observation group had 1 eye with an anterior chamber, and no significant difference in the complications between the groups was evident (P > 0.05). CONCLUSION: Healaflow is of great value in maintaining functional filtration blebs and in controlling and stabilizing intraocular pressure. It is safe and reliable in clinical application, and it helps to reduce the unstable intraocular pressure after glaucoma surgery caused by scar adhesions in the filtration channel.
Department of Glaucoma and Cataract, Aier Eye Hospital Group Hankou Hospital of Wuhan Aier Eye Hospital Wuhan, Hubei, China.
