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Abstract #96102 Published in IGR 22-3
Effect of Postoperative Trimming of the Tube Portion of Ahmed Glaucoma Valve on Corneal Endothelial Cell Loss
Lee KE; Sung KR; Shin JWJournal of Glaucoma 2022; 31: 102-108
PRCIS: We reduced the tube length through small limbal incision in eyes underwent Ahmed glaucoma valve implantation and found rate of corneal endothelial cell density was markedly reduced from -12.2%/year to -3.5%/year after this simple procedure. PURPOSE: To evaluate the effect of postoperative tube tip trimming (TT) after Ahmed glaucoma valve (AGV) implantation on corneal endothelial cell (CEC) loss. METHODS: In this retrospective cohort study, a total of 75 eyes from 67 patients (41 eyes in the AGV implantation only group (AGVG: mean follow up, 42.2±13.8▒mo) and 34 eyes in the TT after AGV implantation group (TAGVG: mean follow up, 64.9±18.5▒mo) were analyzed. TT was performed through a small limbal incision at a mean of 41 months after AGV implantation. Both groups were followed up for at least 1 year and underwent at least two specular microscopic (SM) examinations after AGV implantation and/or TT. RESULTS: In the AGVG, CEC density was reduced from 2247.0±527.3 to 1665.7±643.3▒cells/mm2 (P<0.001). In the TAGVG, it was reduced from 2383.1±619.4 to 1552.9±700.9▒cells/mm2 before TT (mean 41▒mo of follow up) and after TT, to 1394.6±654.7▒cells/mm2 (mean 26▒mo of the follow-up). The reduction rate of CEC density before TT was -12.2±6.5%/year, and this rate was significantly reduced to -3.5±6.9%/year after TT in the TAGVG (P=0.002). The probability of corneal failure defined as a 15% reduction in CEC density was significantly reduced after TT in TAGVG (P=0.038). CONCLUSIONS: Tube tip trimming after AGV implantation markedly reduced the rate of CEC loss without serious complications in eyes with AGV implantation.
Department of Ophthalmology, Asan Medical Center, University of Ulsan, Seoul, Korea.
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