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Abstract #9686 Published in IGR 5-3
Assessment of retinal nerve fiber layer thickness with NFA-GDx following successful scleral buckling surgery
Ozdek S; Lonneville Y; Onol M; Gurelik G; Hasanreisoglu BEuropean Journal of Ophthalmology 2003; 13: 697-701
OBJECTIVE: To assess the effect of retinal detachment (RD) on retinal nerve fiber layer (RNFL) thickness by using a scanning laser polarimeter (NFA-GDx) after successful scleral buckling surgery for the treatment of rhegmatogenous RD. METHODS: Consecutive patients who had had successful scleral buckling surgery in one eye were assessed for RNFL thickness by using NFA-GDx prospectively. Fellow healthy eyes of the patients formed the control group. Eyes with RD surgery were compared with the control group with respect to three variables (superior average, inferior average, and average thickness) of NFA-GDx by using the two-sampled t-test. Additionally, a possible effect of duration of RD on RNFL thickness was assessed with a correlation test. RESULTS: The study group consisted of 16 patients with a mean age of 49.8 years. The mean duration of RD was 28 days. Although the retardation values in the operated eyes were less than those of the control eyes, the difference was not statistically significant (p > 0.05). However, these three values were seen to increase with increased duration of detachment and this correlation was statistically significant (r > 0.5, p < 0.03). CONCLUSIONS: RD seemed to cause minimal or no change in RNFL thickness as determined by GDx variables. The positive correlation between RNFL thickness and duration of RD, however, may be because of the proliferated Müller cells in eyes with RD, which may be responsible for some of the retardation measurements, which may be even more prominent in longstanding RD cases. This needs to be supported by further studies in larger patient groups with longer duration of RD and with histopathological studies.
Dr. S. Ozdek, Gazi University, School of Medicine, Ophthalmology Department, Ankara, Turkey
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
