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Abstract #9697 Published in IGR 5-3
Characteristics of optic disc changes in Taiwanese patients with primary angle-closure glaucoma
Yang CH; Hung PT; Lin LLK; Hsieh JW; Wang TH; Wang IJJournal of the Formosan Medical Association 2003; 102: 183-188
BACKGROUND AND PURPOSE: Primary angle-closure glaucoma (PACG) is the predominant form of glaucoma among Asians. Although numerous studies have been carried out to describe the characteristic optic disc changes in patients with primary open angle glaucoma (POAG) which is the predominant form of glaucoma among Western populations, few studies have evaluated the optic disc changes in patients with PACG. The aim of this study was to elucidate the characteristic intrapapillary and parapapillary disc changes in PACG in a cross-sectional study and to develop a practical approach to the detection of glaucomatous optic disc changes in PACG by ophthalmoscopic examination. METHODS: A total of 103 eyes in 103 PACG patients were studied. Forty-one eyes of 41 age-and sex-matched healthy subjects served as controls. Three glaucoma-trained subspecialists examined stereophotographs of optic disc to evaluate the intrapapillary and parapapillary changes. The differences in PACG and control group eyes were compared. RESULTS: Concentric steep enlargement of the optic disc was found in 99 PACG eyes (96%). Local notching was noted in only three eyes, and vertically oval-shaped cupping of the optic disc in only one eye. Disc hemorrhage was not detected in any eye. Parapapillary atrophy of the alpha zone involving both temporal and nasal side of the optic disc and parapapillary atrophy of beta zone were significantly more frequent in the PACG group. The presence of an alpha zone or a beta zone simultaneously involving both the temporal and nasal side of the optic disc was associated with more severe optic nerve head damage. CONCLUSIONS: The intrapapillary change in the PACG group eyes reflected the development of cupping in PACG patients with small and compact optic disc. The parapapillary atrophy paralleled the intrapapillary optic disc cupping in eye of the PACG group.
Dr. P.-T. Hung, Department of Ophthalmology, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei 100, Taiwan
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
9.3 Primary angle closure glaucomas (Part of: 9 Clinical forms of glaucomas)
