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Abstract #9833 Published in IGR 5-3
Diurnal variation of intraocular pressure in normal-tension glaucoma
Kano K; Kuwayama YNippon Ganka Gakkai Zasshi 2003; 107: 375-379
PURPOSE: Measurement of diurnal variation of intraocular pressure (IOP) is important for precise diagnosis of normal-tension glaucoma (NTG). The authors studied diurnal variation of IOP in NTG patients using a self-measuring tonometer. METHODS: A total of 159 patients (318 eyes) who were diagnosed as having NTG at Osaka Koseinenkin Hospital between 1994 and 2002 measured their own diurnal variation of IOP at home every three hours (eight times a day) using a prototype self-measuring non-contact air-puff tonometer(Hometonometer). RESULTS: Maximum and minimum IOP, and the range of diurnal variation of IOP were 16.8 ± 2.0 mmHg (mean ± SD), 12.8 ± 1.7 mmHg, and 4.0 ± 1.3 mmHg, respectively. Maximum IOP occurred most frequently at noon (24.3%), 9.00 am (21.4%), and 6.00 am (17.4%). In 69.2% of eyes, maximum IOP was found during outpatient clinic hours (9.00 am to 6.00 pm). Minimum IOP occurred most frequently at midnight (34.1%), 3.00 am (22.8%), and 9.00 pm (17.8%). CONCLUSIONS: Approximately 30% of NTG patients have maximum IOP outside outpatient clinic hours, and therefore measuring IOP in the early morning is important for determining the precise diurnal variation of their IOP. The authors hope that a safe self-measuring tonometer with which patients can measure their own IOP will be come commercially available soon, so that we can provide patients with more individualized glaucoma treatment using the appropriate combination of medicines. LA: Japanese
Dr. K. Kano, Department of Ophthalmology, Osaka Koseinenkin Hospital, 4-2-78 Fukushima, Fukushima-ku, Osaka 553-0003, Japan
Classification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)