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Abstract #99188 Published in IGR 22-4
OCT Angiography Face Mask-associated Artifacts During the COVID-19 Pandemic
El-Nimri NW; El-Nimri NW; Micheletti E; Micheletti E; Mohammadzadeh V; Nishida T; Kamalipour A; Zangwill LM; Bowd C; Moghimi S; Weinreb RNJournal of Glaucoma 2022; 31: 399-405
PRCIS: Face mask wearing has no significant effects on artifacts or vessel density measurements in optic nerve head and macular OCT-Angiography scans. PURPOSE: To assess the difference in area of artifacts observed in optical coherence tomography angiography (OCT-A) scans with and without face mask wear and to verify if mask wear interferes with OCT-A vessel density measurements. SUBJECTS AND CONTROLS: 64 eyes of 10 healthy subjects, 4 ocular hypertensive, 8 glaucoma suspects, and 17 glaucoma patients were included. METHODS: High density optic nerve head (ONH) and macula OCT-A scans were obtained in patients with and without surgical masks. Seven different artifacts (motion, decentration, defocus, shadow, segmentation failure, blink, and Z-offset) were quantitatively evaluated by 2 trained graders. The changes in the area (% of scan area) of artifacts, without and with mask wearing, and differences of vessel density were evaluated. RESULTS: Trends of increasing motion artifact area for the ONH scans [4.23 (-0.52, 8.98) %, P=0.08] and defocus artifact area for the macular scans [1.06 (-0.14, 2.26) %, P=0.08] were found with face mask wear. However, there were no significant differences in the mean % area of any artifacts (P>0.05 for all). Further, the estimated mean difference in vessel density in images acquired without and with masks was not significant for any type of artifact. CONCLUSION: Face mask wearing had no significant effect on area of artifacts or vessel density measurements. OCT-A vessel density measurements can be acquired reliably with face mask wear during the pandemic.
Hamilton Glaucoma Center, Shiley Eye Institute, and the Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, CA, United States.
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