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Abstract #9961 Published in IGR 5-3
Efficacy of selective laser trabeculoplasty in the treatment of primary open-angle glaucoma
Gračner T; Pahor D; Gračner BKlinische Monatsblätter für Augenheilkunde 2003; 848-852
BACKGROUND: The aim was to investigate the efficacy of selective laser trabeculoplasty (SLT) for the treatment of primary open-angle glaucoma (POAG) in a prospective clinical study. PATIENTS AND METHODS: In 36 eyes of 36 patients suffering from uncontrolled POAG, treatment was carried out with a frequency-doubled, Q-switched Nd:YAG laser (532 nm). The intraocular pressure (IOP) was measured before the treatment and one day, one week, one month and three, six, 12, 18, 24, 30, 36, 42 and 48 months after. A failure was defined as an IOP reduction of less than 20% from pretreatment IOP, or a progression of visual field or optic disc damage requiring filtering surgery. The hypotensive medication during the study period remained unchanged. RESULTS: Mean follow-up time was 34 months (SD 12,9). Mean pretreatment IOP was 22.9 mmHg (SD 2.1). At the one month of follow-up, the mean IOP reduction was 5.3 mmHg (SD 2.1) or 23.1% and at six months 5.6 mmHg (SD 2.6) or 24.5%. At 12 months of follow-up, mean IOP reduction was 5.6 mmHg (SD 2.3) or 24.5%, and at 24 months 6.2 mmHg (SD 2.5) or 27%. At 36 months of follow-up, the mean IOP reduction was 6.4 mmHg (SD 2.1) or 27.4%, and after 48 months of follow-up, the mean IOP reduction was 5.9 mmHg (SD 2.0) or 25.4%. The success rate after 12 months determined from the Kaplan-Meier survival analysis was 97%, after 24 months 88%, after 36 months 76%, and after 48 months 71%. CONCLUSION: SLT is an effective procedure for the treatment of POAG.
Dr. T. Gračner, Augenabteilung des Lehrkrankenhauses Maribor, Slovenia
Classification:
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)
