advertisement
Abstract #9990 Published in IGR 5-3
Correlation between the early morphological appearance of filtering blebs and outcome of trabeculectomy with mitomycin C
Sacu S; Rainer G; Findl O; Georgopoulos M; Vass CJournal of Glaucoma 2003; 12: 430-435
PURPOSE: To correlate the morphological appearance of filtering blebs in the early postoperative period with the outcome of trabeculectomy with mitomycin C (MMC) during the first postoperative year. PATIENTS AND METHODS: In a prospective study, the morphological appearance of filtering blebs after primary trabeculectomy with adjunctive MMC (0.1 mg/ml for five minutes intraoperatively) was classified; 49 eyes of 49 patients were examined preoperatively, one and three days, one and two weeks, and one, three, six, and 12 months postoperatively. Status of filtering bleb, intraocular pressure (IOP), and number of medications were recorded. RESULTS: One year after surgery all patients had IOP ≤ 21; six patients received antiglaucoma medication. One eye required needling of the filtering bleb because of encapsulation. During the first postoperative year, eyes with conjunctival subepithelial micro cysts, observed in the first and the second postoperative week, had significantly lower mean IOP, than eyes without (11.1 mmHg versus 13.9 mmHg; p:0.0043, ANOVA). Eyes with corkscrew vessels, observed in the first and the second postoperative week, had significantly higher mean IOP, than eyes without during the first postoperative year (13.4 mmHg versus 11.7 mmHg; p:0.0141, ANOVA). CONCLUSION: Classification of filtering blebs after trabeculectomy with MMC may help to disclose patients with an increased failure risk.
Dr. S. Sacu, Department of Ophthalmology, University of Vienna Medical School, Vienna, Austria
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
