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Abstract #10398 Published in IGR 6-1
Multifocal steady-state pattern-reversal electroretinography in glaucoma patients
Lindenberg T; Horn FK; Korth MOphthalmologe 2003; 100: 453-458
AIM: This study was designed to discover whether multifocal steady-state pattern-reversal electroretinography (ERG) is capable of detecting glaucomatous visual field defects. METHODS: Sixteen patients (28 eyes) and ten normal subjects (20 eyes) were examined. Multifocal pattern ERGs were recorded with the RETIscan system and DTL electrodes. The authors produced stimulation with a steady-state checkerboard pattern reversal (three reversals during 171 msec sweep length, congruent with 17.5 reversals/sec). The multifocal pattern ERG amplitudes were evaluated using discrete Fourier transformation (DFT) across three reversals. In cases of advanced glaucoma, the DFT-calculated amplitudes were combined in hemispheres and checked for correlations with corresponding visual field defects. In all binocularly examined persons, side comparisons ('worse' eye versus 'better' eye), and interindividual comparisons (glaucoma versus normal) were carried out. RESULTS: In interindividual comparisons and interocular side comparisons, significant amplitude reductions of the 'worse' eyes were seen in the foveal records. No topographical correlation between multifocal pattern ERG amplitudes and visual field defects could be found. CONCLUSIONS: In glaucomatous visual field defects, multifocal steady-state pattern-reversal ERG using the present stimulation was significantly reduced in its foveal records but seems to be incapable of detecting them topographically. LA: German
Dr. T. Lindenberg, Augenklinik mit Poliklinik der Friedrich-Alexander-Universitat Erlangen-Nuremberg, Erlangen, Germany. Thomas.Lindenberg@augen.imed.uni-erlangen.de
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
