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Abstract #10462 Published in IGR 6-1
Effects of three nasal topical steroids in the intraocular pressure compartment
Bross Soriano D; Hanenberg Milver C; Schimelmitz Idi J; Arrieta Gomez JR; Del Toro RA; Bravo Escobar GOtolaryngology Head and Neck Surgery 2004; 130: 187-191
OBJECTIVE: The purpose of this study was to evaluate whether the use of fluticasone propionate, mometasone furoate, or beclomethasone dipropionate for the treatment of rhinitis produced, as a side effect, an increase in intraocular pressure (IOP); only one printed article states that the increase of secondary IOP is due to the use of local nasal steroids. PATIENTS AND STUDY DESIGN: The authors conducted a comparative, double-blind, experimental, prospective, longitudinal study in which 360 patients were divided at random into four groups; 90 of whom were given a placebo (control group) and the other 270 were divided into three other groups of 90 patients each and given a different local nasal steroid for each group. MEASUREMENT PARAMETERS: All patients had their IOP measured by Goldman's tonometry at three and six weeks, three and six months, and one year after using the placebo or local nasal steroid. RESULTS: Variations were found in the IOP of patients who used a local steroid, with slight elevations in the beclomethasone dipropionate and mometasone furoate groups; however, variations were always within normal limits. CONCLUSIONS: Fluticasone propionate, mometasone furoate, and beclomethasone dipropionate cause variations in the IOP, but these are within normal limits.
Dr. D. Bross-Soriano, Alejandro Dumas 39-PB, Polanco 11560 DF, Mexico City, Mexico
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
