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Abstract #10464 Published in IGR 6-1
Central corneal thickness of normal-tension glaucoma and non-glaucoma populations in ethnic Chinese
Chen HC; Ho JD; Chang SHL; Chen YHS; Wu SCChang Gung medical journal 2004; 27: 50-55
BACKGROUND: The variations in central corneal thickness can influence intraocular pressure measurement. The aim of this study was to determine whether there is a difference in the central corneal thickness between normal-tension glaucoma (NTG) and non-glaucoma populations. METHODS: This prospective study included 33 consecutive patients with NTG and 33 age- and gender-matched healthy subjects as control subjects. NTG patients were grouped according to the refractive error into group 1 (spherical equivalent +2.5 D ˜ -6.0 D) and group 2 (spherical equivalent more than -6.0 D). Central corneal thickness was measured using a ultrasonic pachymeter. The mean central corneal thickness of NTG and healthy subjects were compared using Student's t test and the Wilcoxon rank sum test. RESULTS: The mean (± SD) central corneal thickness in healthy subjects and NTG patients was 554.1 (± 36.3) and 547.2 (± 31.4) μ, respectively. There were no statistical significant differences between these two groups (p = 0.411). The median central corneal thickness in NTG groups 1 and 2 eyes was 545 and 547.5 μ, respectively. This difference was not statistically significant, either (p = 0.799). Ten NTG patients (30%) had high myopia (group 2), and their median age was 38.5 years, which was significantly less than that of group 1 patients (50 years, p = 0.0003). CONCLUSION: This study indicated that there were no significant differences of central corneal thickness between NTG patients and healthy subjects in the authors' clinic.
Dr. S.C. Wu, Department of Ophthalmology, Chang Gung Memorial Hospital, 5, Fushing Street, Gueishan Shiang, Taoyuan, 333, China
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
