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Abstract #10472 Published in IGR 6-1
Postoperative endophthalmitis
Hanscom TAClinical Infectious Diseases 2004; 38: 542-546
Postoperative endophthalmitis remains a serious clinical problem in ophthalmology, with an incidence of ~0.5%. Prognosis is largely determined by the virulence of the offending organism. The endophthalmitis vitrectomy study (EVS) was a prospective, randomized trial that compared various diagnostic and treatment modalities in cases of endophthalmitis that followed cataract surgery. EVS found that vitrectomy was only beneficial for patients presenting with very poor visual acuity and that intravenous antibiotic treatments had no additional benefit, compared with intravitreal antibiotic therapy alone. However, weaknesses of EVS leave these conclusions open to modification in the future. Preoperative application of povidone-iodine preparation to the skin and conjunctiva is the only proven endophthalmitis prophylaxis. Endophthalmitis may be chronic and may follow glaucoma surgery and intravitreal injection of gas and drugs. EVS did not study these issues, although they are associated with specific features that may require alterations in patient management.
Dr. T.A. Hanscom, 2021 Santa Monica Boulevard, #720E, Santa Monica, CA 90404, USA
Classification:
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
