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Abstract #10487 Published in IGR 6-1
The correcting influence of the locus ceruleus on ophthalmic hypertension on hypothalamic origin
Myagkov AV; Danilov GE; Fatykhov IRNeuroscience and Behavioral Physiology 2004; 34: 97-100
Chronic experiments were performed on rabbits to study changes in intraocular pressure (IOP), coefficient of flow conductivity, and chamber fluid minute volume during chronic emotional stress induced by long-lasting repeated electrical stimulation of the ventromedial nucleus of the hypothalamus alone and in combination with electrical stimulation of the locus ceruleus and central gray matter of the periacqueductal matter. Stimulation of the ventromedial nucleus of the hypothalamus was accompanied by increases in IOP and in the production of eye chamber fluid, and a decrease in the coefficient of flow conductivity. Electrical stimulation of the locus ceruleus and central gray matter of the periacqueductal matter led to less marked increases in IOP. Combined stimulation of the hypothalamus and locus ceruleus led to normalization of IOP due to a reduction in the volume of chamber fluid and an increase in the coefficient of flow conductivity.
Dr. A.V. Myagkov, Department of Normal Physiology, Izhevsk State Medical Academy, 199 Revolyutsionnaya Street, 426034 Izhevsk
Classification:
1.2 Population genetics (Part of: 1 General aspects)
