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OBJECTIVE: To evaluate the effect of non-penetrating trabecular surgery (NPTS) with amniotic membrane implant in patients with juvenile glaucoma. METHODS: NPTS with amniotic membrane implant was performed on 32 eyes of 26 patients with juvenile glaucoma aged between 12 approximately 28 years. Intraocular pressure (IOP) was measured pre- and post-operatively by CT-60 non-contact tonometer, intraocular irritations and the bleb appearances were recorded, and the anterior chamber angle of post-operation was observed by gonioscopy. Follow-up was (8.3 ± 4.2) months after surgery. RESULTS: IOP of post-operation was significantly decreased (15.7 ± 3.7) mmHg (1 mmHg = 0.133 kPa; t = 4.82, P < 0.01) compared with that of pre-operation (28.6 ± 7.3) mmHg. The mean number of drug usage was significantly reduced to 0.8 (t = 128, P < 0.01) after surgery when compared with 3.2 before surgery. On the last visit, the IOP was = 21 mmHg in 30 eyes (93.8%), among them, there were 18 eyes (56.3%) without anti-glaucoma medication and 12 eyes (37.5%) with anti-glaucoma compounds. There was a small amount of hyphema that was absorbed in 3 approximately 5 days in 6 eyes. The gonioscopy showed that the remnant trabecular meshwork and Descemet membrane were thinner at the surgical site, and microperforation occurred in the trabecular meshwork in 5 eyes. The complications such as flat chamber, inflammation and choroidal detachment were not observed. There was no significant difference in visual acuity between pre- and post-operation. CONCLUSIONS: NPTS with amniotic membrane implant effectively controls elevated IOP in patients with juvenile glaucoma and reduced the number of anti-glaucoma drug usage without significant post-operative complications. NPTS with amniotic membrane implant is an effective and new method for the treatment of patients with juvenile glaucoma. LA: Chinese
Department of Ophthalmolgy, People's Hospital of Rizhao City, Shandong Province, Rizhao 276800, China. Email: L3366916@163169.net
12.8.3 Non-perforating (Part of: 12 Surgical treatment > 12.8 Filtering surgery)