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Abstract #12033 Published in IGR 7-1
Medication use and retinal vessel diameters
Wong TY; Knudtson MD; Klein BE; Klein R; Hubbard LDAmerican Journal of Ophthalmology 2005; 139: 373-375
PURPOSE: To study the influence of different medications on retinal vessel diameters. DESIGN: Cross-sectional study. METHODS: Retinal photographs in the Beaver Dam Eye Study (n = 4926, aged 43 to 84 years) were digitized, and the diameters of retinal vessels were measured. Participants' current medications were recorded at the examination. RESULTS: There were few significant associations between medication use and retinal vessel diameters. After adjusting for age, blood pressure, and other factors, participants who were using topical beta-blocker eyedrops had narrower retinal arteriolar (P = .05) and venular (P = .006) diameters than nonusers. Systemic beta-blocker was not associated with retinal vessel diameter size. CONCLUSION: We found few associations between current medication use and retinal vessel diameter. Retinal vessels were narrowed in those taking antiglaucoma medications, most strikingly in those prescribed topical beta-blockers, although such a relationship could not be established among those using systemic beta-blockers.
Dr. T.Y. Wong, Centre for Eye Research Australia, University of Melbourne, East Melbourne 3002, Victoria, Australia. twong@unimelb.edu
Classification:
11.1 General management, indication (Part of: 11 Medical treatment)