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Abstract #12103 Published in IGR 7-1
Evaluation of topical brinzolamide switched from dorzolamide for glaucoma
Hasegawa K; Takahashi T; Kawase KJapanese Journal of Clinical Ophthalmology 2005; 59: 215-219
We evaluated the comfort and compliance of brinzolamide twice daily switched from dorzolamide thrice daily in 25 eyes of 25 glaucoma patients. The series comprised primary open-angle glaucoma 17 eyes, normal-tension glaucoma 3 eyes, capsular glaucoma 1 eye, primary closed-angle glaucoma 1 eye, and late-onset developmental glaucoma 3 eyes. All had been treated by multiple medications. After 8 weeks of brinzolamide, 20 patients preferred brinzolamide and 5 patients preferred dorzolamide. Both medications showed stickiness and white eyelid secretion, dorzolamide was less irritable. Better compliance resulted from use of brinzolamide because of lesser frequency of instillation. LA: Japanese
Dr. K. Hasegawa, Department of Ophthalmology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1193, Japan
Classification:
11.5.2 Topical (Part of: 11 Medical treatment > 11.5 Carbonic anhydrase inhibitors)
