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Abstract #13591 Published in IGR 8-2

Analysis of late-onset bleb-belated complications following trabeculectomy with mitomycin C

Zhang D-X; Shi C-Y; Liu S-W
International Journal of Ophthalmology 2005; 5: 1186-1189


AIM: To study the incidence and management of late-onset bleb-related complications following trabeculectomy with mitomycin C. METHODS: We performed a retrospective analysis on 65 eyes of 65 glaucoma patients who underwent trabeclectomy with mitomycin from May 1994 to May 2000. The Kaplan-Meier survival method was used to estimate the probability of a bleb leak, blebitis or endophthalmitis. RESULTS: The average follow-up was 5.6a (range, 2.5-7.1a), 16 eyes (16/65, 24.6%) experienced a bleb leak; 5 eyes (5/65, 7.7%) had an episode of blebitis. Endophalmitis occurred in 1 eye; 1 eye had combined complicate; 9 eyes (9/65, 13.8%) experienced persistent hypotony. A Kaplan-Meier survival analysis estimated the 5a probability of developing a bleb leak, blebitis, endophthalmitis to be 40.0%. Most eyes were successfully treated with office-based measures, and some eyes ultimately underwent surgical revision. CONCLUSION: There is signif icant morbidity associated with trabeculectomy with mitomycin C, and 40.0% of these eyes might develop one of these complications. The inolated bleb leak seems to be a relatively benign condition. If we can manage the complications promptly and precisely, bleb leaks could be repaired; infected eyes were controlled after treatment, and normal IOP could be obtained. LA: Chinese

Dr. D.-X. Zhang, Department of Ophthalmology, Xi'an Jaotong University, Xi'an 710061 Shaanxi Province, China


Classification:

12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)



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