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AIM: To test the ability of multifocal visual evoked potential (mfVEP) in the detecting of glaucoma by comparing the mfVEP recorded from normal subjects and glaucoma patients. METHODS: The mfVEP of 32 normal eyes (n = 21) and of 58 eyes (n = 37) with primary glaucoma were recorded with the Vision Monitor electrophysical apparatus by the second kernel analysis and to determine the correlation of the topographic location between them. RESULTS: There were significant variability (the coefficient of variation was 43.05%) in mfVEP RMS amplitude in the normal subjects; The RMS amplitude of eyes with glaucoma were smaller than that of the normal eyes and significantly statistical difference were found in the relatively center (namely the 0°-10° ring zone) and in superior nasal quadrant (P < 0.05) while there were no significantly statistical differences of the latency time between them. CONCLUSION: The normal subjects have large individual variability of mfVEP responses. The RMS amplitude of the mfVEP of glaucomatous eyes descends, especially in center zone and superior nasal quadrant.
Dr. P.-B. Wang, Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008 Hunan Province, China
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)