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PURPOSE: Visualization of the anterior chamber angle is an important diagnostic method in patients with angle-closure glaucoma. In this study, optical coherence tomography (OCT) was used to image the angle width, the iris configuration, and the iris thickness in patients with angle-closure glaucoma. METHODS: Thirteen eyes of 11 patients suffering from angle-closure glaucoma were studied with slitlamp-adapted OCT. All patients were treated with Nd:YAG laser iridotomy. The angle width (°), the angle opening distance (AOD) (μm), and the iris thickness (μm) were measured with OCT. The configuration of the iris was classified as steeply convex, convex, or flat. RESULTS: The mean angle width was preoperatively 5.1 ± 5.0° (0-15°) and enlarged significantly (p = 0.007) to 10.4 ± 5.5° (0-19°) postoperatively. The AOD changed from 71 ± 55 μm (0-157 μm) preoperatively to 143 ± 74 μm (0-256 μm) postoperatively (p < 0.001). The mean iris thickness was 338 ± 33 μm. With the exception of two eyes the predominant iris configuration changed from convex to flat. CONCLUSIONS: OCT allowed visualization and noninvasive assessment of the anterior chamber angle region in patients with angle-closure glaucoma. Our results suggest that goniometry with OCT could improve the evaluation in patients with narrow or closed anterior chamber angles. LA: German
Dr. C. Wirbelauer, Klinik für Augenheilkunde, Vivantes Klinikum Neukölln, Rudower Strasse 48, 12313 Berlin, Germany
6.9.2 Optical coherence tomography (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)