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PURPOSE: To address the efficacy of fat-removal orbital decompression to reduce intraocular pressure in patients with Graves disease. METHODS: This cohort study included 64 eyes of 39 patients with Graves disease. Thirteen men and 36 women, with a mean age of 52.5 years (range, 27 to 80 years), underwent fat-removal orbital decompression. Intraocular pressure (applanation) and proptosis (Hertel exophthalmometry) were prospectively investigated before surgery and 1 week and 6 months after surgery. RESULTS: The volume of resected fat was 6.4 ± 4.5 (3 to 12) ml. The intraocular pressure in primary position decreased from 19.3 ± 4.4 mmHg to 17.0 ± 2.9 mmHg at 1 week (p < 0.001) and 15.9 ± 3.7 mmHg at 6 months (p < 0.001). Mean proptosis dropped from 24.3± 2.5 mm before surgery to 19.9±3.0 mm at 1 week (p < 0.01), and 19.9 ±3.1 mm at 6 months (p < 0.01). Intraocular pressure decrease neither correlated to the volume of resected fat nor to proptosis reduction. CONCLUSIONS: Fat removal reduces intraocular pressure in patients with Graves disease, with no correlation to the volume of resected fat.
Dr. P.Y. Robert, Department of Ophthalmology, CHU Dupuytren, Limoges Cedex, France
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy