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Abstract #14654 Published in IGR 8-4
Long-term outcome of trabeculectomy with adjunct mitomycin-C for neovascular glaucoma
Ota T; Murayama K; Shimada Y; Ota Y; Yoneya SJapanese Journal of Clinical Ophthalmology 2006; 60: 1637-1641
PURPOSE: To evaluate the long-term outcome of trabeculectomy for neovascular glaucoma with adjunct use of mitomycin C. OBJECTS AND METHOD: This retrospective study was made on 50 eyes of neovascular glaucoma that received mitomycin C-assisted trabeculectomy. Vitrectomy was performed on 38 eyes. Another series of similarly treated 37 eyes of primary open-angle glaucoma (POAG) served as control. Outcome after surgery was evaluated by survical curve analysis of Kaplan-Meier setting 20 mmHg of intraocular pressure as criterium without topical medication. RESULTS: The 3-year survival rate without medication was 51.3% in POAG and 32.3% in neovascular glaucoma. The difference was not significant. Survival rate with topical medication was 59.7% and 77.7% respectively. The difference was significant. There was no difference in 3-year survival rate between eyes with or without prior vitrectomy. CONCLUSION: Mitomycin C-assisted trabeculectomy was useful in neovascular glaucoma but was less effective than in POAG. LA: Japanese
Dr. T. Ota, Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama-cho, Iruma 350-0495, Japan
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
9.4.5.1 Neovascular glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)