advertisement
Abstract #15879 Published in IGR 2-3
Correlation between high-pass resolution perimetry and standard threshold perimetry in subjects with glaucoma and ocular hypertension
Ister M; Capris P; Altieri M; Zingirian M; Traversi CEInternational Ophthalmology 1999; 23: 99-103
PURPOSE: To evaluate the correlation between high-pass resolution perimetry (HRP) and standard threshold perimetry in patients with glaucoma or ocular hypertension. METHODS: Thirty-one glaucomatous patients and 37 ocular hypertension subjects with previous perimetric examination experience were consecutively recruited, and one eye of each patient was selected at random. Glaucomatous patients were classified as having primary open-angle glaucoma when they had an abnormal visual field and/or an abnormal optic nerve head (ONH)/retinal nerve fiber layer (RNFL) typical of glaucoma, open angle at gonioscopy, and no clinically apparent secondary causes for their glaucoma. Ocular hypertension subjects were defined as having an intraocular pressure (IOP) >21 mmHg on no treatment, normal visual field, normal ONH and RNFL, elevated IOP without any treatment. All subjects were examined with the Humphrey Field Analyzer (HFA) 640, program central 30-2 (Humphrey systems, San Leandro, CA), and with HRP, Ophthimus version 2.4, ring program (Nikon-HighTech Vision, Göteborg, Sweden). Visual field indices were obtained with both systems: for HFA, mean deviation (MD), corrected pattern standard deviation (CPSD), and short-term fluctuation (SF), while for HRP, global deviation (GD), local deviation (LD), form index (FI), and neural capacity (NC). The data were analyzed by descriptive analysis, Student's t test with Bonferroni's correction, or the Mann-Whitney non-parametric test and Pearson or Spearman's correlation coefficient. RESULTS: A significant correlation was found between MD and GD (r = -0.81), CPSD and LD (r = 0.87), and PSD and LD (r = 0.72). NC was significantly correlated with MD (r = 0.76), and GD (r = -0.94). FI was significantly correlated with PSD (r = -0.58), CPSD (r = -0.72), and LD (r = -0.56). When the same data were analyzed for the glaucomatous group only, similar results were found; in the ocular hypertensive group, no significant correlation was found except between NC and MD (r = 0.52). CONCLUSIONS: HRP indices vary comparably with HFA indices. Parameters such as NC and FI were significantly correlated with standard visual field indices of both HFA and HRP. Although the clinical applications for FI are not yet clear, NC could detect both early glaucomatous damage and age-related changes.
Dr. M. Ister, Department of Neurological and Visual Sciences, Ophthalmology B, University of Genoa, Genoa, Italy
Classification:
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
