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Abstract #15880 Published in IGR 2-3
Pathologic findings in late endophthalmitis after glaucoma filtering surgery
Beck AD; Grossniklaus HE; Hubbard B; Saperstein D; Haupert CL; Margo CEOphthalmology 2000; 107: 2111-2114
OBJECTIVE: To report the clinicopathological features of four eyes enucleated for late-onset bleb-related endophthalmitis. STUDY DESIGN: Retrospective case series. MATERIAL: Four enucleated eyes. METHODS: The clinical and histopathological features of four patients who underwent enucleation for late-onset endophthalmitis after glaucoma filtering surgery were reviewed. RESULTS: The eyes were enucleated for endophthalmitis one to five years after trabeculectomy. Two of the four eyes had trabeculectomy with adjunctive mitomycin C. All four eyes had streptococci cultured from the aqueous and/or vitreous. Common pathological features included inflammation involving the anterior segment, lens and choroid. One eye exhibited focal granulomatous uveitis. CONCLUSIONS: Late-onset endophthalmitis after glaucoma filtering surgery is often due to streptococcal species and rapidly progresses over a few days. Phacoanaphylaxis with associated granulomatous uveitis may contribute to the poor prognosis in this setting.
Dr. H.E. Grossniklaus, L.F. Montgomery Eye Pathology Laboratory, BT 428 Emory Eye Center, 1365 Clifton Road NE, Atlanta, GA 30322, USA
Classification:
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
