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Abstract #15983 Published in IGR 2-3
The effect of three kinds of anti-glaucoma eye drops on ocular blood flow
Zhau J; Mao J; Sui KChinese Journal of Ophthalmology 2000; 36: 425
OBJECTIVE: Surveying the changes of ocular blood flow by continuous anti-glaucoma eye drops. METHODS: Thirty-two patients attending a glaucoma clinic were divided into three groups: one treated by 0.5% timolol, one by 0.5% levobunolol, and the third by 0.1% dipivefrine, twice a day. Each patient underwent retinal and choroidal angiography before and after the medication. The authors also carried out intra- and inter-observer reproducibility tests to verify the credibility of the method used to determine the ocular blood flow. All the data were analyzed by Student's t test. RESULTS: The reproducibility test revealed that this method was creditable. Timolol and levobunolol were able to decrease the choroidal blood flow significantly, there was a trend for the optic blood flow to be decreased after continuous application of timolol eye drops. Dipivefrine did not induce any significant change in ocular blood flow, except for mild artery constriction. CONCLUSION: These results suggest that it is necessary to be careful in choosing the correct anti-glaucoma eye drops when ischemia plays an important role in the glaucomatous damage.LA: Chinese
Dr. J. Zhau, Ophthalmology Department, Peking Union Medical College Hospital, Beijing 100730, China
Classification:
11.7 Treatment of bloodflow (Part of: 11 Medical treatment)
