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Abstract #17444 Published in IGR 9-2
Long-term effect of trabeculectomy combined with MMC on repeated surgery for glaucoma
Ming P; Zhou B; Li Z-RInternational Journal of Ophthalmology 2007; 7: 526-528
AIM: To evaluate the long-term effect of trabeculectomy combined with MMC on repeated surgery for glaucoma. METHODS: This retrospective study included 19 cases (21 eyes) with glaucoma patients for trabeculectomy and followed up for 1- 3 years. Definition of effect for surgery were determined as: A) Nice: intraocular pressure (IOP) ≤ 16 mmHg, visual acuity ≥ 0.3, optic nerve and vision field without advanced damage; B) Good: no antiglaucoma medication or only local medication of topical antiglaucoma drops, IOP ≤ 21 mmHg, visual acuity ≥ 0.1-0.25 and optic nerve and vision field without advanced damage; C) No effect: IOP could not been controlled and also with antiglaucoma topical drops. Definition of successful surgery: A and B is successful. RESULTS: The study included 19 cases (21 eyes) with 100% patients with a follow-up of over one year, 16 cases (18 eyes) with 76% patients with a follow-up of over three years. After surgery, the average IOP was significantly lowered to 16.3 ± 4.1 mmHg from 35.8 ± 5.32 mmHg (P≤ 0.001), there were 11 cases in which the IOP was 13 ± 2.7 mmHg, eight cases in which the IOP was controlled with topical antiglaucoma drops. There was no significantly difference in the cup-disc ratio (C/D) and the visual acuity after surgery was 0.02-0.5. There were eight eyes with 38% patients who had a visual acuity of > 0.3, 17 eyes with 81% patients who had a visual acuity of > 0.1. Based on the criteria for successful surgery: A) 8 eyes; B) 9 eyes; C) 4 eyes. The successful rate of surgery was 86% at one year, 76% at three years. Among 21 eyes for early complication: there were 6 eyes with the corneal epithelial defect, 9 eyes with lower IOP and shallow anterior chamber, two eyes with choroidal detachment,1 eye with ciliary block glaucoma. After followed-up for three years, there were 5 eyes with advanced cataract, 2 eyes were underwent cataract surgery combined with antiglaucoma because of uncontrolled IOP. CONCLUSION: Trabeculectomy combined MMC has a high successful rate in treatment of glaucoma with good long-term effect, Observation from repeated surgery also showed satisfactory results. LA: Chinese
Dr. P. Ming, Department of Ophthalmology, Ninth People's Hospital of Chongqing, Chongqing 400700, China. pingguomingping@yahoo.com.cn
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)