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Abstract #17578 Published in IGR 9-2
Selective laser trabeculoplasty in the primary open-angle glaucoma
Qian S-H; Sun X-HZhonghua Yi Xue Za Zhi 2007; 87: 118-120
OBJECTIVE: To investigate the efficacy and safety of selective laser trabeculoplasty (SLT) in the treatment of primary open angle glaucoma (POAG). METHODS: In a prospective non-randomized clinical study, 63 patients (85 eyes) with POAG and medically uncontrolled intraocular pressure (IOP) underwent SLT. A total of 50 ± 5 adjacent but nonoverlapping spots were placed over inferior 180(degrees) of the trabecular meshwork using a 532 nm, Q-switched, Nd: YAG laser at energy levels ranging from 0.6 - 1.8 mJ per pulse. After SLT, the eyes continued to receive the identical drug regimen. All patients were observed before and 1, 2 hours, 1, 7 and 14 days, and 1, 2, 3, 6, 9, 12, 18, and 24 months after the treatment. RESULTS: The average pre-operative IOP was (25 (±) 4) mmHg (1 mmHg = 0.133 kPa). The mean IOP reduction from baseline were 8.1 mmHg (32.0%) 1 day after the SLT, 5.6 mmHg (22.1%) 7 days after the SLT, 4.7 mmHg (18.6%) 14 days after the SLT, 5.5 mmHg (21.7%) 1 month after the SLT, 5.1 mmHg (20.2%) 2 months after the SLT, 5.9 mmHg (23.3%) 3 months after the SLT, 5.2 mmHg (20.6%) 6 months after the SLT, 4.0 mmHg (15.8%) 9 months after the SLT, 4.2 mmHg (16.6%) 12 months after the SLT, 3.8 mmHg (15.0%) 18 months after the SLT, and 3.3 mmHg (13.0%) 24 months after the SLT (P < 0.01 or 0.05). Adverse reactions were minimal, including conjunctival injection, mild anterior chamber reaction, and transient pressure spike. CONCLUSION: SLT is a safe, and effective method of reducing IOP in POAG patients. LA: Chinese
Dr. S.-H. Qian, Eye and ENT Hospital, Fudan University, Shanghai 200031, China
Classification:
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)
