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Abstract #17627 Published in IGR 9-2
A placebo controlled double blind clinical trial of mitomycin C in primary trabeculectomy in Ethiopian patients
Girma T; Courtright P; Mengistu F; Tinebeb Tamirat Birhanu ZEthiopian medical journal 2006; 44: 253-256
Objective: To determine if surgery with mitomycin has an increased success rate in reducing introccular pressure after trabeculectomy in Ethiopian patients. METHODS: A double blind clinical trial using mitomycin C and placebo during primary trabeculectomy was carried out on 31 patients and 31 controls. 31 patients and 28 controls completed the study period. Post operative intra ocular pressure and post operative complications were assessed. RESULTS: There was no statistically significant difference in the postoperative intra ocular pressure in both groups (p = 0.6 95%CI). However there was a statistically significant higher rate of complications in the cases when compared to the controls (p = .002 95%CI). CONCLUSION: A controlled study with adequate power using different dosages of mitomycin is recommend.
Dr. T. Girma, 8051 Keating Av.2N, Skokie, IL 60076, USA
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
