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BACKGROUND: The aim of the study was to assess the frequency of asymptomatic left ventricular dysfunction in primary open-angle glaucoma patients. PATIENTS AND METHODS: Two-dimensional and pulsed Doppler echocardiography of transmittal flow was performed on 31 glaucoma patients and 27 controls. RESULTS: No significant difference was found in early (E) and late (A) transmittal filling velocity, velocity time integral E wave (VTIE) and A wave (VTIA), left ventricular end-diastolic pressure, pulmonary capillary wedge pressure, left ventricular ejection fraction (EF) and fractional shortening (FS). A significant difference was found in ratio E/A (p = 0.04) and ratio VTIA/VTIE (p = 0.05), although all obtained values were within the 95% confidence limit for the corresponding age. CONCLUSIONS: This study tends to indicate the possibility of dysfunction of myocardial relaxation in glaucoma patients, which might be partially attributed to systemic vascular dysregulation.
Dr L. Bojic, Clinic Hospital Split, Eye Clinic, Split University, Soltanska 1, 21000 Split, Croatia. deni@kbsplit.hr
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)