advertisement
Abstract #18947 Published in IGR 3-1
High-resolution ultrasonic imaging and characterization of the ciliary body
Silverman RH; Lizzi FL; Ursea BG; Rondeau MJ; Badr Eldeen N; Kaliscz A; Lloyd HO; Coleman DJInvestigative Ophthalmology and Visual Science 2001; 42: 885-894
PURPOSE: To develop a means for noninvasive in vivo visualization of the ciliary process using very-high-frequency (50 MHz) ultrasound, and to develop quantative morphological descriptors that may relate to physiological function. METHODS: The region of the ciliary body was scanned with very-high-frequency ultrasound, both in rabbits and in normal human subjects. Data were acquired in a series of planes so that the spacing between them was less than the beam width of the transducer in its focal plane. Three-dimensional perspective images were constructed, representing the anatomy of the angle region, including the ciliary processes. The automatically detected boundaries of the ciliary processes were analyzed to compute their periphery, area, shape factor, and fractal dimension. These measures were compared between the human and the rabbit eye and analyzed for periodicities related to the spacing of successive processes. RESULTS: Three-dimensional images allowed visualization of the radial arrangement of the processes. All biometric descriptors were significantly difference between the rabbit and human eye and showed periodicities consistent with spacing between processes. CONCLUSIONS: The methods described in this report are sensitive descriptors of the state of the ciliary processes. These techniques may be of value in the measurement of changes in the ciliary body associated with disease, medical therapy, and aging.
Dr R.H. Silverman, Department of Ophthalmology, Weill Medical College of Cornell University, 1300 York Avenue, Room A855, New York, NY 10021, USA. prof@boodle.med.cornell.edu
Classification:
2.9 Ciliary body (Part of: 2 Anatomical structures in glaucoma)
