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Glaucoma optic neuropathy involves biomechanical damage. Ischemia and mechanics stress within lamina cribrosa (LC) play an important role in axonal damage. Optic disc biomechanical conditions including geometry, material properties, boundary conditions and mechanical loading were analyzed according to basic principles of biomechanism. Computer-assisted 3-D finite element models of optic disc, the stresses, deformation and strains in optic connective tissue, prelaminar and postlaminar neural tissue, LC, scleral canal from a range of normal and elevated intraocular pressures were summarized. The relation between optic disc biomechanical characteristic and glaucomatous vision loss were studied and etiology of glaucoma and the susceptibility of an individual optic disc to intraocular pressure were reviewed. LA: Chinese
Dr. D. Qian, Department of Ophthalmology, Affiliated First Hospital, Guangxi Medical University, Nanning 530021, China. jinhua56@hotmail.com
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
2.3 Sclera (Part of: 2 Anatomical structures in glaucoma)