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Abstract #19573 Published in IGR 9-3
Effect of age on the development of a latanoprost-induced increase in iris pigmentation
Arranz-Marquez E; Teus MAOphthalmology 2007; 114: 1255-1258
PURPOSE: To study the effect of patient age on the incidence of latanoprost-induced increases in iris pigmentation. DESIGN: Prospective observational observer-masked study. PARTICIPANTS: Thirty-six patients younger than 60 years (group 1) and 36 patients older than 75 years (group 2) with primary open-angle glaucoma. METHODS: We photographed both irises of each patient before and 6 months after unilateral latanoprost therapy. The basal iris colors were matched in both groups. MAIN OUTCOME MEASURES: Iris heterochromia identification at the 6-month evaluation of the photographs. RESULTS: Twenty-eight patients (77.78%) in group 2 developed an increase in iris pigmentation compared with eight patients (22.22%) in group 1 (P = 0.0001, chi-square test). CONCLUSIONS: Age seems to be an important risk factor for latanoprost-induced iris color change.
Dr. E. Arranz-Marquez, Vissum Hospital Oftalmológico Madrid, Madrid, Spain. e.arranzmarquez@gmail.com
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
2.8 Iris (Part of: 2 Anatomical structures in glaucoma)
