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Abstract #20076 Published in IGR 9-4
Increased retinal blood flow in patients with active Graves' ophthalmopathy
Perri P; Campa C; Costagliola C; Incorvaia C; D'Angelo S; Sebastiani ACurrent Eye Research 2007; 32: 985-990
PURPOSE: To investigate retinal blood flow by Heidelberg retina flowmeter in patients with active Graves' ophthalmopathy. MATERIALS AND METHODS: Thirty patients with active Graves' ophthalmopathy in euthyroid state and thirty normal controls were enrolled in this study. All subjects underwent heart rate, systolic and diastolic blood pressure detection, complete ophthalmological examination, Hertel's exophthalmometry, and retinal blood flow analysis by Heidelberg retina flowmeter. Patients additionally underwent automated threshold perimetry and extraocular muscle thickness measurement by A-scan ecography. RESULTS: A significant statistical difference was found in exophthalmometry (P < 0.001), intraocular pressure (P < 0.001) and retinal blood flow (P < 0.05) between patients and controls. In patients, muscle enlargement was significantly correlated with retinal blood flow (r = 0.49, P = 0.005) and proptosis (r = 0.37, P = 0.04). A significant positive correlation (r = 0.52, P = 0.002) was also found between intraocular pressure and proptosis. CONCLUSIONS: Active Graves' ophthalmopathy patients present an increased retinal blood flow.
Dr. P. Perri, Eye Clinic, University of Ferrara, Ferrara, Italy
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
6.1 Intraocular pressure measurement; factors affecting IOP (Part of: 6 Clinical examination methods)
