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Abstract #21787 Published in IGR 10-3
Vogt-Koyanagi-Harada syndrome in a Greenlandic Inuit
Ostergaard J; Goldschmidt E; Andersen NActa Ophthalmologica 2008; 86: 576-578
PURPOSE: To report a case of Vogt-Koyanagi-Harada syndrome (VKH) in an Inuit. METHODS: We carried out a medical evaluation and human leucocyte antigen (HLA) genotyping. RESULTS: A 36-year-old male Inuit developed severely decreased vision, intense headache and vertigo over a 3-week period. Ocular examination revealed panuveitis with bilateral serous retinal detachment and optic nerve head oedema. There was no history of ocular trauma or evidence suggestive of other disease entities. The patient responded well to high-dose systemic prednisolone. Vitiligo presented late in the course. CONCLUSIONS: This case report describes the first published case of VKH in a patient of Inuit ancestry. The patient was homozygous for HLA-DR4, a genotype previously associated with VKH.
Dr. J. Ostergaard, Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Classification:
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
