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Abstract #23018 Published in IGR 11-1
The role of lens parameters in primary angle closure glaucoma
Feng Z-H; Zhou A-Y; Han D-G; Wang X-H; Sun N-XInternational Journal of Ophthalmology 2009; 9: 61-63
AIM: To research the role the lens dimensions played on the pathogenesis of primary angle-closure glaucoma. METHODS: Forty-one eyes of 21 patients with acute primary angle-closure glaucoma (PACG) and 40 eyes of 20 normal individuals with narrow chamber angle were examined. The lens parameters and other anatomical parameters of anterior segment were calculated using B ultrasound, computer image processing software and ultrasound biomicroscopy (UBM). The lens parameters were compared between the patients and normal subjects. Correlation analysis was used to determine the relationship between lens parameters and anterior chamber depth and parameters of anterior chamber angle. RESULTS: Compared with the normal eyes, the eyes of PACG had thicker lens, steeper curvature of anterior lens surface and the relative more anterior position of lens. There were statistically significant differences (P <0.01). There were no significant differences between the lens diameter, lens volume and the radius of curvature of posterior lens surface of PACG and those of normal controls (P >0.05). The PACG radii of curvature of anterior lens surface and the relative position of lens had significantly positive correlation with anterior chamber depth (ACD), angle-open distance at 500μm (AOD(500)), trabecular iris angle (TIA) (P <0.01). CONCLUSION: The occurrence of PACG is relevant to the abnormal anatomical structures of lens, including the thicker lens, steeper curvature of anterior lens surface, and the relative more anterior position of lens. The later two factors are main factors of shallowing of anterior chamber and secondary closure of chamber angle. Lens diameter and lens volume and the curvature of posterior lens surface are not close relevant with PACG. LA: Chinese
Dr. Z.-H. Feng, Department of Ophthalmology, School of Medicine, Xi'an Jiaotong University, Xi'an 710004 Shaanxi Province, China. fzhwyh@126.com
Classification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
2.10 Lens (Part of: 2 Anatomical structures in glaucoma)
