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Abstract #23584 Published in IGR 11-2
Presence of crystalline lens as a protective factor for the late development of open angle glaucoma after vitrectomy
Luk FO; Kwok AK; Lai TY; Lam DSRetina (Philadelphia, Pa.) 2009; 29: 218-224
PURPOSE: To evaluate the late development of open angle glaucoma (OAG) after vitrectomy and to compare the rate of postvitrectomy OAG development in phakic and pseudophakic eyes. METHODS: Retrospective case series of 101 eyes of 101 patients who had vitrectomy for idiopathic epiretinal membrane or idiopathic macular hole with a follow-up duration of more than 6 months. Eligible patients were assessed for new development of OAG during the follow-up period. Patients were separated into two groups based on the lens status at the end of the vitrectomy for statistical analysis using Kaplan-Meier survival analysis with log-rank test and Cox regression analysis. RESULTS: The mean follow-up duration was 51 months (range, 6-80 months). Of the 101 eyes, 8 (7.9%) eyes developed OAG during the follow-up period. Phakic eyes were less likely to develop OAG after vitrectomy compared with pseudophakic eyes, with 2% and 13%, respectively (log-rank test, P = 0.025). The result remained statistically significant after adjustment for age, refractive error and the use of gas tamponade (adjusted odds ratio = 0.09, P = 0.038). CONCLUSION: The presence of the crystalline lens may be protective against the late development of OAG after vitrectomy.
F.O. Luk. Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, The People's Republic of China. fiona_luk@yahoo.com
Classification:
9.4.11.5 Glaucomas associated with vitreoretinal surgery (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.11 Glaucomas following intraocular surgery)