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Abstract #24612 Published in IGR 11-4
Long-term effectiveness of laser peripheral iridectomy on treatment of chronic angle-closure glaucoma
Xu D; Li J; Liu XChinese Ophthalmic Research 2009; 27: 805-808
Objective: Laser peripheral iridectomy was a common management for chronic angle-closure glaucoma in clinic, but its long-term effectiveness is below understood. This study was to evaluate the long-term effect of LPI on chronic angle-closure glaucoma. Methods: The regular follow-up result of 116 eyes from 66 patients received laser peripheral iridectomy for chronic angle-closure glaucoma was retrospectively studied. The intraocular pressure (IOP), optic disc change, chamber angle state,visual field, medicine history and further treatment before and after laser peripheral iridectomy were recorded and analysed. Results: During the mean follow-up period of 73.2 months, IOP was 28.5 mmHg in the patients with only laser peripheral iridectomy and 23.5 mmHg in the patients with laser peripheral iridectomy + medicine, respectively. After laser peripheral iridectomy,no more medicine treatment was needed in 20 eyes (17%), and 49 eyes (42%) showed a well-controlled IOP under the use of laser peripheral iridectomy + medicine. IOP of 47 eyes (41%) was over 21 mmHg in the patients with laser peripheral iridectomy + medicine. Further surgery was performed in 35 eyes, including trabeculectomy in 30 eyes and laser peripheral iris plasty and selective laser trabeculoplasty in 5 eyes. The mean duration between laser peripheral iridectomy and further surgery was 18.66 months. Eyes cured only by LPI were 17 and 3 in IOP <21 mmHg group and (greater-than or equal to)21 mmHg group, showing a significant difference between them ((chi)(2) = 6.136, P = 0.013). Number of failure to surgery and medicine treatment was 15 eyes and 32 eyes, respectively ((chi)(2) = 26.68, P < 0.001) at the end of follow-up. Conclusion: Most of chronic angle-closure glaucoma patients need further treatment after laser peripheral iridectomy,and some even need trabeculectomy for control of IOP. So it is necessary for patients with chronic angle-closure glaucoma, especially those with high IOP, to visit doctor regularly. LA: Chinese
D. Xu. Chinese Academy of Medical Science, Department of Ophthalmology, Peking Union Medical College Hospital, Beijing 100730, China. guaji@yahoo.com
Classification:
12.2 Laser iridotomy (Part of: 12 Surgical treatment)
9.3.5 Primary angle closure (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
