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Abstract #25076 Published in IGR 12-1
Intracranial pressure and glaucoma
Berdahl JP; Allingham RRCurrent Opinions in Ophthalmology 2010; 21: 106-111
PURPOSE OF REVIEW: Glaucoma remains a disease with an unclear basic pathophysiology. The optic nerve travels through two pressurized regions: the intraocular space and the intracranial space. Some authors have suggested that the relationship between intraocular pressure and intracranial pressure may play a fundamental role in the development of glaucoma. RECENT FINDINGS: Recent studies have shown that intracranial pressure is lower in patients with glaucoma and normal-tension glaucoma. Conversely, intracranial pressure appears to be elevated in patients with ocular hypertension. Early mathematical modelling studies have suggested that the counterbalance provided by intracranial pressure would be an important factor in the development of glaucoma. SUMMARY: The relationship between intraocular pressure and intracranial pressure may play an important role in the development of glaucoma.
aVance Thompson Vision, 1310 W 22nd Street, Sioux Falls, South Dakota, USA bDuke University Eye Center, Durham, North Carolina, USA.
Classification:
1.3 Pathogenesis (Part of: 1 General aspects)
2.16 Chiasma and retrochiasmal central nervous system (Part of: 2 Anatomical structures in glaucoma)
