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Abstract #25202 Published in IGR 12-1
The effect of oral magnesium therapy on visual field and ocular blood flow in normotensive glaucoma
Aydin B; Onol M; Hondur A; Kaya MG; Ozdemir H; Cengel A; Hasanreisoglu BEuropean Journal of Ophthalmology 2010; 20: 131-135
PURPOSE: To evaluate the effect of oral magnesium therapy on ocular blood flow and visual field perimetry indices in patients with normotensive glaucoma (NTG). METHODS: Fifteen patients with NTG (study group) received 300 mg oral magnesium citrate for 1 month, while 15 patients with NTG (control group) received no treatment. Blood magnesium level measurement, visual field analysis, and color Doppler imaging of the orbital vessels were done before treatment and at 1 month. RESULTS: In the study group, mean deviation improved from -3.7+/-1.9 (mean +/- standard deviation) at baseline to -2.5+/-1.8 at 1 month (p<0.05), and pattern standard deviation improved from 3.6+/-2.3 at baseline to 2.8+/-2.6 at 1 month (p<0.05). Color Doppler imaging indices did not change after magnesium therapy. CONCLUSIONS: Oral magnesium therapy may provide improvement in the visual field, but does not seem to affect ocular blood flow in patients with NTG. Other mechanism than increased ocular blood flow may be responsible for the improvement in the visual field with oral magnesium therapy.
Ophthalmology Department, Fatih University, Turkey. baydunus@yahoo.com
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
11.14 Investigational drugs; pharmacological experiments (Part of: 11 Medical treatment)
6.6.1 Conventional manual (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)