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Abstract #25395 Published in IGR 12-1

The anterior chamber depth measurement of primary angle-closure glaucoma with UBM and pentacam

Liang J; Liu W; Ji J
Chinese Ophthalmic Research 2010; 28: 75-78


Background: Nowadays, glaucoma is the major cause of irreversible blindness worldwide and the second cause of global visual loss. To accurately obtain the anterior chamber depth (ACD) is of helpful for screening primary angle-closure glaucoma (PACG). Objective: The aim of this study is to explore the difference and agreement in the measurement of ACD between Scheimplug Imaging System (Pentacam) and ultra-sonographic biomicroscope (UBM). Methods: Seventy-seven eyes of 77 PACG patients aged (69.96 (plus or minus)7.87) were divided into two groups. Thirty-seven eyes with acute primary angle-closure glaucoma (APACG) were assigned to group 1, and forty eyes with chronic primary angle-closure glaucoma (CPACG) were assigned to group 2. Central ACD was measured with Pentacam and UBM, respectively. The Bland-Altman method was used to evaluate the agreement of the two methods. Results: The ACD values measured by Pentacam and UBM were (1.6467 (plus or minus) 0.2687) mm and (1.5601 (plus or minus)0.2677) mm respectively in APACG, indicating a significant difference (t = - 7.259 ,P < 0.01) and a positive linear correlation between the results of these two methods (r = 0.939, P < 0.01). The ACD values measured by Pentacam and UBM were (2.0622 (plus or minus)0.2317) mm and (1.9648 (plus or minus)0.2176) mm respectively in CPACG eyes with a significant difference between them(t =-10.433, P< 0.01) and a significant linear correlation between these two outcomes (r=0.967 ,P < 0.01). The Bland-Altman method showed that the two modalities had comparable results for ACD. Conclusion: Pentacam, as a new 3-dimensional mathematical model of the anterior segment, presents some different results from UBM in the measurement of ACD, but it is not clinically significant. Combination of Pentacam and UBM may be available for the clinical measurement of ACD. LA: Chinese

J. Liang. Tianjin Medical University Eye Center, Tianjin 300070, China. tjykzx@yahoo.com.cn


Classification:

6.8.1 Anterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)



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