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Purpose: To evaluate the intraocular pressure (IOP) reducing effect of a fixed combination of 0.005% latanoprost and 0.5% timolol in patients with an IOP of 30 mmHg or higher. Design: Prospective, randomized clinical trial. Participants: Twenty-eight patients. Methods: Patients had received no prior medical glaucoma treatment. Routine ophthalmic examinations and visual field tests were performed before and after treatment for each patient. Results: Mean IOP was 32.28 (plus or minus) 0.92 mmHg before treatment. Mean IOP levels were 18.75 (plus or minus) 0.68 for the first day, 17.96 (plus or minus) 0.90 for the first week and 17.64 (plus or minus) 0.66 for the first month after treatment. Conclusion: A fixed combination of latanoprost 0.005% and timolol 0.5% is effective in significantly reducing IOP in glaucoma patients with an IOP greater than 30 mmHg.
Y. B. Ozkurt. Sen Apartmani, Korkut sokak, Dumankaya evleri, A1B blok, 9/7, Kozyatagi/Istanbul, Turkey. yeldaozkurt@yahoo.com
11.13.4 Betablocker and prostaglandin (Part of: 11 Medical treatment > 11.13 Combination therapy)