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Abstract #25720 Published in IGR 12-2
Non-arteritic anterior ischemic optic neuropathy and glaucomatous optic neuropathy
Nakamura MNeuro-Ophthalmology Japan 2010; 27: 33-40
Non-arteritic anterior ischemic optic neuropathy (NAION) is a painless, sudden-onset optic neuropathy, which is characterized by pale edema of optic disc at the acute phase and inflammatory optic atrophy at the chronic phase. Transient hypoperfusion of short posterior ciliary artery is presumably responsible for the development of NAION. In addition to systemic risk factors such as diabetes and circulatory disturbances, small disc or absence of cup, which is referred to as a crowded disc, is a local risk factor. Glaucomatous optic neuropathy (GON) is characterized by posterior displacement of the lamina cribrosa and the enlargement of the optic disc cup. However, these alterations of the optic nerve head are not specific signs for GON but are observed in approximately 10% of other types of optic neuropathies. Taking together with facts that both diseases have circular disturbance as a risk factor and can manifest altitudinal hemifield defect, NAION and GON share, at least in part, common mechanisms for the development of diseases. LA: Japanese
M. Nakamura. Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Classification:
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
