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Abstract #25958 Published in IGR 12-2
Correlation of cardiovascular diseases and risk factors with severity of glaucoma at presentation
Tham CCY; Baig N; Lam DSCEuropean Heart Journal, Supplement 2010; 12: S34
Objective: To identify any correlation between cardiovascular diseases and cardiovascular risk factors with severity of glaucoma at presentation. Methods: Consecutive primary angle closure glaucoma patients were recruited and interviewed at presentation. Patients with significant cataract were excluded. History of hypertension, diabetes mellitus, hyperlipidaemia, ischaemic heart disease, cerebrovascular accident, and smoking (primary and secondary) were specifically questioned. The average of the mean deviations (MD) by Humphrey automated perimetry of the two eyes was taken as one of the indices of glaucoma severity. Patients with and without cardiovascular history were compared in these indices using Student's t-test. Results: One hundred and seventy-six glaucoma patients (116 females, 60 males) were recruited. Mean age(plus or minus)standard deviation (SD) was 70.8(plus or minus)11.1 years (range 32-94 years). Sixty-seven patients (38.1%) had history of one or more cardiovascular diseases or risk factors. Patients with cardiovascular history had an MD(plus or minus)SD of -18.37(plus or minus)8.91 db (range, -3.52 to -30.19 db), while patients without cardiovascular history had an MD of -14.58(plus or minus)9.55 db (range, -3.52 to -30.12 db; P = 0.02). Conclusions: Glaucoma patients with one or more cardiovascular diseases or risk factors have more severe glaucoma at presentation.
C.C.Y. Tham. Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong KongHong Kong.
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
