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Abstract #26452 Published in IGR 12-3
Different types of optic disc shape in patients with advanced open-angle glaucoma
Nakazawa T; Fuse N; Omodaka K; Aizawa N; Kuwahara S; Nishida KJapanese Journal of Ophthalmology 2010; 54: 291-295
See also comment(s) by Marcello Nicolela •
Purpose: To study the characteristics of patients with advanced open-angle glaucoma. Methods: A hospital-based retrospective study was performed. Advanced glaucoma was defined as visual acuity of 0.3 or less, or mean deviation of -24 dB or less. First, we screened patients with advanced glaucoma and classified their glaucoma types. For patients with open-angle glaucoma (OAG), including both primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), disc types were classified into four groups: focal ischemic (FI), myopic glaucomatous (MY), senile sclerotic (SS), and generalized cup enlargement (GE). Results: After checking the medical history of 750 glaucoma patients, we classified 141 (18.8%) as having the advanced stage of the disease. The proportion of patients with advanced OAG was 47% (28% POAG, 19% NTG). The classification of optic disc appearances in OAG patients showed that in patients with POAG the predominant disc type was GE (P = 0.0012) and in those with NTG it was MY (P < 0.0001). Conclusion: In OAG patients in this study with severe glaucomatous damage, the predominant disc phenotype was GE in patients with POAG and MY in those with NTG.
T. Nakazawa. Department of Ophthalmology, Tohoku University, Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. ntoru@oph.med.tohoku.ac.jp
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
