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Abstract #26700 Published in IGR 12-3
Case series of premature neonates with congenital glaucoma
Couser NL; Patel G; Thiagarajah C; Jones LS; Kern MDJournal of AAPOS 2010; 14: 14
Introduction: To evaluate the incidence and clinical features of coexistent congenital glaucoma and retinopathy of prematurity (ROP). Methods: A retrospective review was performed of all ROP consults undertaken at one Hospital from 1997 to 2005. All cases of coexistent congenital glaucoma and ROP were noted. Variables such as birth weight, maternal risk factors, exposure to oxygen, birth complications, stage and zone of ROP, and characteristics of congenital glaucoma were evaluated. Results: Five of 242 patients had concurrent ROP and congenital glaucoma. ROP ranged from stage I to stage III. One of five patients was treated with laser for threshold ROP. Four of 5 patients were treated with trabeculotomy for congenital glaucoma. Conclusions: The incidence of congenital glaucoma in the neonates with ROP was 2%, much higher than the estimated overall incidence of 1/10,000-15,000. The increased incidence of congenital glaucoma may support the theory of developmental arrest of the anterior segment in premature infants. Additionally, ROP may in some way increase the risk of congenital glaucoma in patients with mal- or under-developed angles. Prematurity itself may be an independent risk factor for congenital glaucoma.
N.L. Couser.
Classification:
9.1.1 Congenital glaucoma, Buphthalmos (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
