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Purpose: Childhood glaucoma is an uncommon pediatric condition that can be categorized into primary, secondary, and acquired subtypes. The purpose of this study is to describe the population-based incidence and clinical characteristics of glaucoma in patients<20 years of age during a 40-year period. Methods: The medical records of all patients (<20 years) diagnosed with glaucoma or glaucoma suspect, as residents of Olmsted County, Minnesota from January 1, 1965, through December 31, 2004, were retrospectively reviewed. Results: Thirty children were diagnosed with glaucoma and 24 with glaucoma suspect during the 40-year study period. The ageand sex- adjusted incidence of childhood glaucoma was 2.29 (95% confidence interval [CI], 1.47-3.12) per 100,000 person years, with the following types and incidences: 19 acquired (1.46/100,000; 95% CI, 0.80-2.12), 6 secondary (0.45/100,000; 95% CI, 0.08-0.82), and 5 primary glaucoma (0.38/100,000; 95% CI, 0.05-0.72). The mean age at diagnosis was 10.5 years (range, 15 days to 19.7 years) with a mean initial intraocular pressure of 26.9 mmHg (range, 14.0-40.0 mmHg). The birth prevalence of primary congenital glaucoma during the 40-year period was 1 in 68,254 births or 1.46 per 100,000 births (95% CI, 0.03-8.16). Twenty-four glaucoma suspects were identified, yielding an incidence of 1.9 per 100,000 in patients <20 years of age (95% CI, 1.14-2.66). Conclusions: The incidence of childhood glaucoma in this population was 2.29 per 100,000 or 1 in 43,575 for patients<20 years of age. Acquired and secondary forms of glaucoma were the most common while congenital and juvenile glaucoma were rare.
B.G. Mohney.
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
1.1 Epidemiology (Part of: 1 General aspects)